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Phenotypic variations dictate the intracellular compartmentalization of doxorubicin in normal human bone marrow cells

✍ Scribed by Esther Aghaï; Zoltán A. Tökés

Publisher
Springer
Year
1990
Tongue
English
Weight
609 KB
Volume
25
Category
Article
ISSN
0344-5704

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Sister chromatid exchange (SCE) was studied in bone marrow cells of six healthy individuals. Compared with peripheral blood lymphocytes, a remarkably low and constant rate of SCEs was observed, ranging from 3.64 to 4.65 per metaphase. The lower incidence of SCE can be related only partly to the hig