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The rate of sister chromatid exchange in normal human bone marrow cells

✍ Scribed by R. Becher; C. G. Schmidt; Gabriele Theis; D. K. Hossfeld

Publisher
Springer
Year
1979
Tongue
English
Weight
193 KB
Volume
50
Category
Article
ISSN
0340-6717

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✦ Synopsis

Sister chromatid exchange (SCE) was studied in bone marrow cells of six healthy individuals. Compared with peripheral blood lymphocytes, a remarkably low and constant rate of SCEs was observed, ranging from 3.64 to 4.65 per metaphase.

The lower incidence of SCE can be related only partly to the higher contraction of bone marrow cells and the shorter exposure time to BUdR. Rather, a cell-specific phenomenon is suggested.

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