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Phenotypic features of Huntington's disease-like 2

✍ Scribed by Ruth H. Walker; Joseph Jankovic; Elizabeth O'Hearn; Russell L. Margolis

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
59 KB
Volume
18
Category
Article
ISSN
0885-3185

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✦ Synopsis

Abstract

Huntington's disease‐like 2 is an autosomal dominantly inherited disorder due to an expansion of trinucleotide repeats. It resembles classic Huntington's disease in clinical phenotype, inheritance pattern, and neuropathological features. We highlight the clinical features of this disorder, including chorea, dystonia, parkinsonism, and cognitive deficits. © 2003 Movement Disorder Society

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