## Abstract Adult Tโcell leukemia/lymphoma (ATLL) patients are highly immunocompromised, but the underlying mechanism responsible for this state remains obscure. Recent studies demonstrated that __FOXP3__, which is a master control gene of naturally occurring regulatory T (Treg) cells, is expressed
Phenotypic and functional relationship between adult T-cell leukemia cells and regulatory T cells
โ Scribed by Matsubara, Y; Hori, T; Morita, R; Sakaguchi, S; Uchiyama, T
- Book ID
- 110056151
- Publisher
- Nature Publishing Group
- Year
- 2005
- Tongue
- English
- Weight
- 75 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0887-6924
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## Abstract The leukemic Tโcelis of the six patients with Tโcell chronic lymphocytic leukemia (TโCLL), four with CD4 and CD45Rโpositive (CD4+ CD45R\*) TโCLL and two with CD8 and CD45Rโpositive (CD8+ CD45R+) TโCLL phenoโtype were studied for detailed immunologic phenotypic and functional characteris