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Phenobarbital Enhances the Aldehyde Dehydrogenase Activity of Rat Hepatocytes in Vitro and in Vivo

✍ Scribed by Marselos, Marios ;Michalopoulos, George

Book ID
114800702
Publisher
Wiley (Blackwell Publishing)
Year
2009
Weight
518 KB
Volume
59
Category
Article
ISSN
0001-6683

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Enhancement of aldehyde dehydrogenase ac
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✍ Marios Marselos; Stephen C. Strom; George Michalopoulos πŸ“‚ Article πŸ“… 1986 πŸ› Springer 🌐 English βš– 707 KB

Aldehyde dehydrogenase was measured in primary cultures of hepatocytes obtained with a two-step collagenase perfusion either from human hepatic tissue or from livers of Fisher rats. Basal enzyme activity declines gradually as a function of time in culture, but remains at all times higher when measur