Phenethyl isothiocyanate induces Ca2+ movement and cytotoxicity in PC3 human prostate cancer cells
β Scribed by Chung-Ren Jan; Chung-Yi Chen; Shu-Chi Wang; Soong-Yu Kuo
- Book ID
- 118482570
- Publisher
- Elsevier
- Year
- 2011
- Tongue
- English
- Weight
- 695 KB
- Volume
- 42
- Category
- Article
- ISSN
- 1876-1070
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## Abstract This study was undertaken to investigate the mechanism by which phenethyl isothiocyanate (PEITC), a natural compound from cruciferous vegetables, exhibits antitumor effect on prostate cancer cells. Cell proliferation, cell cycle, Western blot, gene transfer, and reporter assays were use
## Abstract The present study evaluated the effects of thimerosal, a vaccine preservative, on cytosolic free Ca^2+^ concentrations ([Ca^2+^]~i~) in human prostate cancer cells (PC3). Thimerosal (10β200βΒ΅M) increased [Ca^2+^]~i~ in a concentrationβdependent manner. The Ca^2+^ signal was reduced part