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Phenacyl esters of acetic acid derivatives and their application for the synthesis of 2-oxo-4-phenyl-5-(phenylhydrazono)-2,5-dihydro-furan-3-derivatives

✍ Scribed by Jan Hlaváč; Pavel Hradil; Radek Mělnický; Lubomír Kvapil; Petr Šlézar; Martin Grepl——; Pavel Hradil; Antonín Lyčka; Martin Grepl

Publisher: Journal of Heterocyclic Chemistry
Year: 2008
Tongue: English
Weight: 437 KB
Volume: 45
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570450529

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✦ Synopsis

Abstract

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Coupling of various substituted phenacyl acetates 1 and diazonium salts 3 was studied. If the phenacyl acetates were substituted by an electronaceptor group such as CN or COOEt 3‐substituted phenyl‐5‐(phenyl‐hydrazono)‐5__H__‐furan‐2‐ones 4 were formed. Also synthesis of aza and diaza analogs is described. The compounds were characterized using MS and NMR spectroscopy.

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