Phase transitions of sterols and sterol—lecithin sterol—lecithin mixtures
✍ Scribed by Peter G. Barton
- Book ID
- 103041391
- Publisher
- Elsevier Science
- Year
- 1976
- Tongue
- English
- Weight
- 303 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0009-3084
No coin nor oath required. For personal study only.
✦ Synopsis
Sterols exhibit reversible htermal transitions below their melting points which are dependent on the state of hydration and on the structure of the aliphatic substituent at C17. The endotherm exhibited by cholesterol can be abolished by mixing with hydrated phospholipids at molar ratios below 1 : 1 but reappears in a metastable form at molar ratios between 1 : 1 and 2 : 1.
📜 SIMILAR VOLUMES
Paramagnetic resonance of cholestane and three fatty acid probes is used to measure the effects of the addition of cholesterol, 7-dehydrocholesterol and ergosterol to egg phosphatidylcholine bilayers. At low concentrations we find that all three sterols effectively align the bilayers. However, conce