The objective of this study was to determine the susceptible day for the developmental toxicity of din-butyl phthalate (DBP). Pregnant rats were given a single dose of DBP by gastric intubation at 1500 mg kg ุ1 on one of days 6-16 of pregnancy. A significant increase in the incidence of postimplanta
Phase specificity of developmental toxicity after oral administration of mono-n-butyl phthalate in rats
โ Scribed by M. Ema; R. Kurosaka; A. Harazono; H. Amano; Y. Ogawa
- Publisher
- Springer
- Year
- 1996
- Tongue
- English
- Weight
- 576 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0090-4341
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
In two Segment II Teratology studies, timed-pregnant Crl:CD[BR] (Sprague-Dawley) rats were treated orally (gastric intubation) on days 6-15 of gestation with ibutilide fumarate (ibutilide), a class Ill antiarrhythmic that has been shown to increase the refractory period and action potential duration
The objective of this study was to determine the susceptible day for the developmental toxicity of butyl benzyl phthalate (BBP) by a single administration on one of the days during organogenesis. Pregnant rats were given a single dose of BBP by gastric intubation at a dose of 1000 mg kg(-1) on one o
## Abstract The developmental toxicity of the three main metabolites of __N__โmethylโ2โpyrrolidone (NMP) was studied in SpragueโDawley rats. Pregnant rats were given 5โhydroxyโ__N__โmethylโ2โpyrrolidone (5โHNMP; 0, 250, 500, 750 or 1000 mg kg^โ1^ day^โ1^), __N__โmethylsuccinimide (MSI; 0, 500, 750,