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Phase-shifting effects of pituitary adenylate cyclase activating polypeptide on hamster wheel-running rhythms

✍ Scribed by Hugh D. Piggins; Elliott G. Marchant; Donna Goguen; Benjamin Rusak


Book ID
117471730
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
153 KB
Volume
305
Category
Article
ISSN
0304-3940

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The neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) is present in many regions of the adult and developing brain as are receptors for PACAP. PACAP stimulates different signalling cascades in neurons, involving cAMP, MAP kinase, and calcium. These characteristics suggest that