Phase I/II trial of weekly cisplatin, etoposide, and irinotecan chemotherapy for metastatic lung cancer: JCOG 9507
β Scribed by Sekine, I; Nishiwaki, Y; Kakinuma, R; Kubota, K; Hojo, F; Matsumoto, T; Ohmatsu, H; Goto, K; Kodama, T; Eguchi, K
- Book ID
- 109997502
- Publisher
- Nature Publishing Group
- Year
- 2003
- Tongue
- English
- Weight
- 109 KB
- Volume
- 88
- Category
- Article
- ISSN
- 0007-0920
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## Abstract There is no standard therapy for relapsed small cell lung cancer (rSCLC). We evaluated the efficacy and toxicity of a new triplet consisting of irinotecan (100 mg/m^2^ Days 1 and 15 q28), cisplatin (40 mg/m^2^ Days 1 and 15 q28) and mitomycin (6 mg/m^2^ d1 q28) administered to a maximum
## Abstract ## BACKGROUND The authors attempted to determine the maximum tolerated dose (MTD) of gemcitabine in combination with etoposide and cisplatin as a chemotherapy regimen and investigated the safety and antitumor activity with the recommended doses of gemcitabine with etoposide and cisplat