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Randomised phase II trial of irinotecan plus cisplatin vs irinotecan, cisplatin plus etoposide repeated every 3 weeks in patients with extensive-disease small-cell lung cancer

✍ Scribed by Sekine, I; Nokihara, H; Takeda, K; Nishiwaki, Y; Nakagawa, K; Isobe, H; Mori, K; Matsui, K; Saijo, N; Tamura, T


Book ID
109999415
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
108 KB
Volume
98
Category
Article
ISSN
0007-0920

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Phase II trial of irinotecan and cisplat
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## Abstract ## BACKGROUND. A Phase II trial of irinotecan and cisplatin (IP) with early concurrent radiotherapy was performed in limited‐disease small‐cell lung cancer (LD‐SCLC) to evaluate the efficacy and toxicity. ## METHODS. For untreated LD‐SCLC patients, irinotecan (60 mg/m^2^, Days 1, 8,