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Phase I/II study of the anti-oestrogen zindoxifene (D16726) in the treatment of advanced breast cancer. A Cancer Research Campaign Phase I/II Clinical Trials Committee study

โœ Scribed by Stein, RC; Dowsett, M; Cunningham, DC; Davenport, J; Ford, HT; Gazet, J-C; von Angerer, E; Coombes, RC


Book ID
109836547
Publisher
Nature Publishing Group
Year
1990
Tongue
English
Weight
649 KB
Volume
61
Category
Article
ISSN
0007-0920

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Phase I/II study of bisantrene in childh
โœ Movassaghi, Nasser ;Krivit, William A. ;Krailo, Mark D. ;Hammond, G. Denman ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 328 KB

A phase I/II study of bisantrene using a 3-week schedule was undertaken in 171 children with refractory leukemias and solid tumors. The doses ranged from 190 to 430 mg/m2. The maximum tolerated dose for children with solid tumors and acute leukemias was 280 mg/m2 and 360 mg/m2 every 3 weeks, respect