Phase II trial to topotecan in hepatocellular carcinoma: A Southwest Oncology Group study
β Scribed by James G. Wall; Jacqueline K. Benedetti; Mark A. O'Rourke; Ronald B. Natale; John S. Macdonald
- Book ID
- 110229823
- Publisher
- Springer US
- Year
- 1997
- Tongue
- English
- Weight
- 23 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0167-6997
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract ## BACKGROUND The objective of this study was to estimate the time to treatment failure and survival rate of the threeβdrug combination of doxorubicin, cisplatin, and ifosfamide as primary and postoperative, adjunctive treatment for teenagers and adults with osteosarcoma (OS). ## METH
Patient with advanced adenocarcinoma of the pancreas and no prior chemotherapy were treated on a Phase II trial of mitoxantrone. Doses were adjusted for hepatic dysfunction as defined by bilirubin. Twenty-four patients with a bilirubin less than or equal to 1.5 mg% received mitoxantrone 12 mg/m2 i.v