## Abstract ## BACKGROUND The aim of the current randomized Phase II study was to investigate the efficacy and safety of capecitabine combined with irinotecan as firstβline treatment in metastatic colorectal carcinoma (CRC). ## METHODS A total of 140 patients received capecitabine at a dose of 1
β¦ LIBER β¦
Phase II trial of two different irinotecan schedules with pharmacokinetic analysis in patients with recurrent glioma: North Central Cancer Treatment Group results
β Scribed by Marta Santisteban; Jan C. Buckner; Joel M. Reid; Wenting Wu; Bernd W. Scheithauer; Matthew M. Ames; Sara J. Felten; Daniel A. Nikcevich; Martin Wiesenfeld; Kurt A. Jaeckle; Evanthia Galanis
- Book ID
- 106481147
- Publisher
- Springer US
- Year
- 2008
- Tongue
- English
- Weight
- 235 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0167-594X
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## Abstract ## BACKGROUND The objective of this study was to test the response rate and toxicity of alternating chemotherapy in previously untreated patients with extensiveβstage small cell lung carcinoma (SCLC). ## METHODS Patients with histologically proven, extensiveβstage SCLC, with a perfor