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Phase II trial of temsirolimus in patients with metastatic breast cancer

✍ Scribed by Gini F. Fleming, Cynthia X. Ma, Dezheng Huo, Husain Sattar, Maria Tretiakova, L. Lin, Olwen M. Hahn, F. O. Olopade, R. Nanda, Philip C. Hoffman, M. J. Naughton, Timothy Pluard, Suzanne D. Conzen, Matthew J. Ellis


Book ID
118796611
Publisher
Springer US
Year
2012
Tongue
English
Weight
235 KB
Volume
136
Category
Article
ISSN
0167-6806

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The Eastern Cooperative Oncology Group conducted a phase II study of lonidamine in patients with metastatic breast cancer. The drug was given orally to a maximum daily dose of 340 mg/m 2. Forty-two patients were entered on study. One partial response was observed; there were no life-threatening toxi