Phase II study of ionidamine in patients with metastatic breast cancer
β Scribed by H. Ian Robins; Donna S. Neuberg; Al B. Benson; Kishan J. Pandya; Douglass C. Tormey
- Publisher
- Springer US
- Year
- 1990
- Tongue
- English
- Weight
- 193 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0167-6997
No coin nor oath required. For personal study only.
β¦ Synopsis
The Eastern Cooperative Oncology Group conducted a phase II study of lonidamine in patients with metastatic breast cancer. The drug was given orally to a maximum daily dose of 340 mg/m 2. Forty-two patients were entered on study. One partial response was observed; there were no life-threatening toxicities. The results of this study are compared to two similar phase II trials.
π SIMILAR VOLUMES
The National Cancer Institute of Canada (NCIC) Clinical Trials Group conducted a phase II study of the oral antiandrogen flutamide in 33 patients with metastatic breast cancer. Eight patients had received no prior systemic therapy for their metastatic disease and 13 had only one site of metastasis.