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Phase II study of deoxyspergualin in metastatic breast cancer

✍ Scribed by Kapil Dhingra; Vicente Valero; Lia Gutierrez; Richard Theriault; Daniel Booser; Frankie Holmes; Aman Buzdar; Giuseppe Fraschini; Gabriel Hortobagyi

Publisher
Springer US
Year
1994
Tongue
English
Weight
553 KB
Volume
12
Category
Article
ISSN
0167-6997

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The Eastern Cooperative Oncology Group conducted a phase II study of lonidamine in patients with metastatic breast cancer. The drug was given orally to a maximum daily dose of 340 mg/m 2. Forty-two patients were entered on study. One partial response was observed; there were no life-threatening toxi