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Phase II trial of irinotecan (CPT-11) plus raltitrexed (ZD) in patients with previously untreated, advanced colorectal cancer (ACC)

✍ Scribed by Aparicio, J.; Vicent, J.; Maestu, I.; Galán, A.; Bosch, C.; Busquier, I.; Garcerá, S.; Llorca, C.; Campos, J.; Balcells, M.


Book ID
122755296
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
160 KB
Volume
37
Category
Article
ISSN
0959-8049

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## Background: This multicenter, phase ii trial was performed to evaluate the antitumor activity and toxicity of irinotecan (cpt-11) in patients with metastatic colorectal carcinoma that had recurred or progressed after 5-fluorouracil (5-fu)-based chemotherapy. ## Methods: Cpt-11 was given as a 9