## Background: This multicenter, phase ii trial was performed to evaluate the antitumor activity and toxicity of irinotecan (cpt-11) in patients with metastatic colorectal carcinoma that had recurred or progressed after 5-fluorouracil (5-fu)-based chemotherapy. ## Methods: Cpt-11 was given as a 9
β¦ LIBER β¦
A randomised phase II multicentre trial of irinotecan (CPT-11) using four different schedules in patients with metastatic colorectal cancer
β Scribed by Schoemaker, N E; Kuppens, I E L M; Moiseyenko, V; Glimelius, B; Kjaer, M; Starkhammer, H; Richel, D J; Smaaland, R; Bertelsen, K; Poulsen, J P; Voznyi, E; Norum, J; Fennelly, D; Tveit, K M; Garin, A; Gruia, G; Mourier, A; Sibaud, D; Lefebvre, P; Beijnen, J H; Schellens, J H M; ten Bokkel Huinink, W W
- Book ID
- 109998279
- Publisher
- Nature Publishing Group
- Year
- 2004
- Tongue
- English
- Weight
- 123 KB
- Volume
- 91
- Category
- Article
- ISSN
- 0007-0920
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