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Phase II trial of ICRF-187 in patients with acquired immune deficiency related Kaposi's Sarcoma (AIDS-KS)

✍ Scribed by A. Chachoua; M. Green; J. Wernz; F. Muggia

Book ID: 118287222
Publisher: Springer US
Year: 1989
Tongue: English
Weight: 346 KB
Volume: 7
Category: Article
ISSN: 0167-6997
DOI: 10.1007/bf00173762

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## Abstract ## BACKGROUND. Matrix metalloproteinases (MMPs) are overexpressed in Kaposi sarcoma (KS). The safety and efficacy of a novel, orally bioavailable MMP inhibitor, BMS‐275291, was evaluated in patients with human immunodeficiency virus‐associated KS and the correlation between changes in