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Phase II AIDS Malignancy Consortium (AMC) trial of imatinib in AIDS-associated Kaposi’s sarcoma (KS)

✍ Scribed by Henry B Koon, Kord Honda, Jeannette Y Lee…

Book ID
120697353
Publisher
BioMed Central
Year
2010
Tongue
English
Weight
188 KB
Volume
5
Category
Article
ISSN
1750-9378

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✍ Brett T. Brinker; Susan E. Krown; Jeannette Y. Lee; Ethel Cesarman; Amy Chadburn 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 85 KB

## Abstract ## BACKGROUND. Matrix metalloproteinases (MMPs) are overexpressed in Kaposi sarcoma (KS). The safety and efficacy of a novel, orally bioavailable MMP inhibitor, BMS‐275291, was evaluated in patients with human immunodeficiency virus‐associated KS and the correlation between changes in