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Phase II trial of erlotinib with temozolomide and radiation in patients with newly diagnosed glioblastoma multiforme

✍ Scribed by David M. Peereboom; Dale R. Shepard; Manmeet S. Ahluwalia; Cathy J. Brewer; Neeraj Agarwal; Glen H. J. Stevens; John H. Suh; Steven A. Toms; Michael A. Vogelbaum; Robert J. Weil; Paul Elson; Gene H. Barnett

Publisher: Springer US
Year: 2009
Tongue: English
Weight: 180 KB
Volume: 98
Category: Article
ISSN: 0167-594X
DOI: 10.1007/s11060-009-0067-2

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## Abstract ## BACKGROUND Currently, the survival of patients age > 70 years with glioblastoma multiforme (GBM) ranges from 4 months to 6 months, although radiotherapy and/or chemotherapy may prolong survival in certain subgroups. Temozolomide is an oral chemotherapeutic agent with efficacy agains

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