Phase II study of thalidomide and radiation in children with newly diagnosed brain stem gliomas and glioblastoma multiforme
โ Scribed by Christopher D. Turner; Susan Chi; Karen J. Marcus; Tobey MacDonald; Roger J. Packer; Tina Young Poussaint; Sridhar Vajapeyam; Nicole Ullrich; Liliana C. Goumnerova; R. Michael Scott; Caitlin Briody; Christine Chordas; Mary Ann Zimmerman; Mark W. Kieran
- Publisher
- Springer US
- Year
- 2006
- Tongue
- English
- Weight
- 199 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0167-594X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## BACKGROUND. Prognosis for the majority of children with brain stem gliomas is dismal. In previous studies, recombinant beta-interferon (@IF) has been shown to be effective for children with recurrent brain stem gliomas and may also act synergistically with radiotherapy (RT). ## METHODS. Thir
## Abstract ## BACKGROUND Currently, the survival of patients age > 70 years with glioblastoma multiforme (GBM) ranges from 4 months to 6 months, although radiotherapy and/or chemotherapy may prolong survival in certain subgroups. Temozolomide is an oral chemotherapeutic agent with efficacy agains
## Background: Diffuse pontine gliomas remain one of the most lethal of pediatric malignancies despite the use of increasingly intensive therapies. we delivered intensive chemotherapy during and following 70.2 gy of hyperfractionated radiation therapy in an attempt to improve survival. ## Procedur
## Abstract ## BACKGROUND Ninety percent of children with diffuse, intrinsic brainstem tumors will die within 18 months of diagnosis. Radiotherapy is of transient benefit to these children, and a potential way to improve its efficacy is to add radiosensitizers. Carboplatin is antineoplastic and ra