Phase II trial of ICRF-187 in children w
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Tribhawan Vats; Barton Kamen; Jeffrey P. Krischer
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Article
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1991
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Springer US
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English
⚖ 280 KB
ICRF-187 is the ( + ) enantiomer of the racemic mixture razoxane . This compound is much more water soluble and thus could be formulated for parental use. The maximum tolerated dose in children after phase I trials was determined to be 3500 mg/MVday x 3 days. A phase II trial of ICRF-187 was done in