27 patients with resistant acute myelogenous leukemia (AML) were treated with AMSA. Three achieved a complete remission, and two a partial remission. Median survival for all patients was 12 weeks and was 16 weeks for responders
Phase II trial of plicamycin and hydroxyurea in acute myelogenous leukemia
β Scribed by Eric Archimbaud; Jacques Troncy; Catherine Sebban; Denis Guyotat; Yves Devaux; Martine French; Michel Moriceau; Jean-Jacques Viala; Denis Fiere
- Publisher
- Springer
- Year
- 1989
- Tongue
- English
- Weight
- 229 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0344-5704
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Treatment of the myeloid blast phase of chronic granulocytic leukemia is still a major problem in clinical hematology. Alternate-day plicamycin and hydroxyurea treatment was reported to induce remissions in the majority of patients with myeloid blast phase by Koller and Miller in 1986 Subsequently w
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