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Phase II trial of 5-fluorouracil, high-dose leucovorin calcium, and dipyridamole in advanced prostate cancer

✍ Scribed by D. Singh; J. H. Doroshow; L. Leong; K. Margolin; S. Akman; J. Raschko; G. Somlo; R. Morgan; J. Harrison; J. Cho; C. Ahn

Book ID
112498097
Publisher
Springer-Verlag
Year
1992
Tongue
English
Weight
425 KB
Volume
119
Category
Article
ISSN
1432-1335

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Background. In a previous Phase I1 trial, the authors showed that a weekly continuous infusion of 5-fluorouracil (5-FU) at a dose of 3.5 g/mz for 48 hours is an active treatment for advanced colorectal cancer. The overall response rate was 38.5%, and the median survival was 12 months. These data wer