## BACKGROUND. This Phase II multicenter study evaluated the efficacy and toxicity of paclitaxel (200 mg/m 2 by 3-hour infusion) with carboplatin (area under the curve 6 mg/mL per minute) administered every 3 weeks as first-line therapy for women with metastatic breast carcinoma. ## METHODS. Eligi
Phase II study of paclitaxel in patients with metastatic breast carcinoma refractory to standard chemotherapy
β Scribed by Edgardo Rivera; Frankie A. Holmes; Debra Frye; Vicente Valero; Richard L. Theriault; Daniel Booser; Ronald Walters; Aman U. Buzdar; Kapil Dhingra; Giuseppe Fraschini; Gabriel N. Hortobagyi
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 83 KB
- Volume
- 89
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## BACKGROUND. Cisplatin-based combination chemotherapy for patients with advanced transitional cell carcinoma (TCC) of the urothelium has limitations, and new therapies need to be evaluated. METHODS. Ifosfamide 1.0 gm/m 2 on Days 1-4 and paclitaxel 135 mg/m 2 by 24-hour infusion on Day 4 were ad
## BACKGROUND. Nearly all cases of metastatic prostate carcinoma progress, after hormonal ablation, to a hormone refractory status. To the authors' knowledge no standard chemotherapy for patients with hormone refractory prostate carcinoma (HRPC) exists. In a prospective study, the efficacy and toxi
## METHODS. Twenty patients with histologically proven Stage IV NSCLC were en-Pennsylvania. rolled in this study. All were treated on an outpatient basis with standard premedication followed by paclitaxel 200 mg/m 2 infused intravenously over 3 hours. Treatments were repeated every 21 days for a