Phase-II-study of fotemustine, cisplatin and high-dose tamoxifen in metastatic malignant melanoma
β Scribed by Semb, K.A.; Aamdal, S.; Bohmann, T.; Lucas, C.; Gerard, B.
- Book ID
- 122008291
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 161 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0959-8049
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by 40 mg to the MTD in groups of 3 patients. DDP (80 mg/m 2 ) was begun on Day ogy/Oncology, Hollings Cancer Center, Medical 2 and repeated weekly for a total of 3 weeks. During Week 4, the patients were University of South Carolina, Charleston, South not treated with DDP but instead evaluated for r
Seventeen patients with disseminated malignant melanoma received a daily oral regimen of tamoxifen, 100 mg/m2. All patients had prior chemotherapy and predominantly visceral involvement. None of the patients had an objective regression and most (71%) had progressive disease at the time of first reas