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Phase II study of a triplet regimen in advanced colorectal cancer using methotrexate, oxaliplatin and 5-fluorouracil

✍ Scribed by Guglielmi, A; Barni, S; Zaniboni, A; Pella, N; Belvedere, O; Beretta, G D; Grossi, F; Frontini, L; Puglisi, F; Labianca, R; Sobrero, A

Book ID
109998282
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
103 KB
Volume
91
Category
Article
ISSN
0007-0920

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A phase II study of sequential methotrex
A phase II study of sequential methotrexate and fluorouracil in advanced colorectal cancer
✍ L. Panasci; J. Ford; R. Margolese πŸ“‚ Article πŸ“… 1985 πŸ› Springer 🌐 English βš– 242 KB

Twenty-nine patients with advanced colorectal cancer were treated with methotrexate (MTX) 200 mg/m2 followed 1 h later by fluorouracil (FU) (1000 mg/m2) and 24 h later by oral leucovorin 20 mg every 6 h for six doses. The cycle was repeated every 2 weeks. Among the 25 evaluable patients there were 2