Patient with advanced adenocarcinoma of the pancreas and no prior chemotherapy were treated on a Phase II trial of mitoxantrone. Doses were adjusted for hepatic dysfunction as defined by bilirubin. Twenty-four patients with a bilirubin less than or equal to 1.5 mg% received mitoxantrone 12 mg/m2 i.v
Phase II evaluation of suramin in advanced renal cell carcinoma: A Southwest Oncology Group study
β Scribed by Louis E Schroder; Danika Lew; Robert C Flanigan; Mario A Eisenberger; Thomas E Seay; Neel Hammond; Burton M Needles; E.David Crawford
- Book ID
- 117724123
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 51 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1078-1439
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## BACKGROUND. Renal cell carcinoma is a common neoplasm that is often refractory to treatment. It is occasionally responsive to immunoniodulating agents including interferon-a, which enhances the effects of 5-fluorouracil upon cells. Combinations of these two drugs have been most frequently tested
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