Phase II clinical trial of capecitabine and gemcitabine chemotherapy in patients with metastatic renal carcinoma
β Scribed by Waters, J S; Moss, C; Pyle, L; James, M; Hackett, S; A'Hern, R; Gore, M; Eisen, T
- Book ID
- 109998304
- Publisher
- Nature Publishing Group
- Year
- 2004
- Tongue
- English
- Weight
- 115 KB
- Volume
- 91
- Category
- Article
- ISSN
- 0007-0920
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## Abstract ## BACKGROUND Metastatic renal cell carcinoma (RCC) has modest response rates to chemotherapy with gemcitabine and 5βfluorouracil (5βFU). Fixed dose rate gemcitabine infusion leads to enhanced intracellular accumulation of drug and possible augmented clinical effect. To determine the t
## Abstract ## BACKGROUND. The purposes of this study were to evaluate efficacy and toxicity of the combination of carboplatin, gemcitabine, and capecitabine in patients with carcinoma of unknown primary site (CUP). ## METHODS. Patients with CUP received carboplatin AUC 5 mg/mL a minute intraven