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Phase I study of paclitaxel poliglumex administered weekly for patients with advanced solid malignancies

โœ Scribed by Monica Mita; Alain Mita; John Sarantopoulos; Chris H. Takimoto; Eric K. Rowinsky; Ofelia Romero; Patrizia Angiuli; Cecilia Allievi; Amy Eisenfeld; Claire F. Verschraegen


Publisher
Springer
Year
2008
Tongue
English
Weight
404 KB
Volume
64
Category
Article
ISSN
0344-5704

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A phase I study of a weekly schedule of
โœ Wallace Akerley; Ritesh Rathore; Neil Ready; Louis Leone; William Sikov; Howard ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 64 KB ๐Ÿ‘ 2 views

## Background: We conducted a phase i study of weekly paclitaxel (p) and carboplatin (c) in patients with advanced malignancies to determine the maximum tolerated dose (mtd) of this combination. ## Methods: Dose levels were escalated independently for patients with and without previous chemothera