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Phase I evaluation of the combination 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU; NSC-409962) and dianhydrogalactitol (DAG; NSC-132313) in patients with advanced neoplastic diseases

โœ Scribed by Creagan, Edward T. ;Eagan, Robert T. ;Rubin, Joseph


Publisher
John Wiley and Sons
Year
1979
Tongue
English
Weight
127 KB
Volume
7
Category
Article
ISSN
0098-1532

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Phase II study of 1,3-Bis (2-chloroethyl
โœ Cary A. Presant; Stephen Hillinger; Carol Klahr ๐Ÿ“‚ Article ๐Ÿ“… 1980 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 466 KB ๐Ÿ‘ 1 views

Eighteen patients with unresectable bronchogenic carcinoma were treated with amphotericin B (7.5 mgim' on day I , I5 mg/m2 on day 2, and 30 mg/m2 on days 3 and 4) plus BCNU (250 mg/m2 on day 4 following amphotericin B) with courses of therapy repeated every 8 weeks. All patients had metastatic disea