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Phase I clinical trials of WR-2721 with alkylating agent chemotherapy

โœ Scribed by John H. Glick; Donna J. Glover; Clare Weiler; Albert Blumberg; Diana Nelson; John M. Yuhas; Morton Kligerman


Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
710 KB
Volume
8
Category
Article
ISSN
0360-3016

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Patients undergoing x-ray therapy to the pelvis have intestinal symptoms proportional to the volume treated and the dose delivered. WR-2721, S-2 (3-aminopropylaminoethyl) phosphorothioic acid, is an organic thiophosphate compound that selectively protects normal tissues against radiation effects. A