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Phase I Clinical Trial Assessing Temozolomide and Tamoxifen With Concomitant Radiotherapy for Treatment of High-Grade Glioma

✍ Scribed by Shilpen Patel; Steven DiBiase; Barry Meisenberg; Todd Flannery; Ashish Patel; Anil Dhople; Sally Cheston; Pradip Amin


Book ID
118455480
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
85 KB
Volume
82
Category
Article
ISSN
0360-3016

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## Abstract ## Background High‐grade gliomas are highly lethal neoplasms representing approximately 20% of all intracranial tumors. Cationic liposome‐mediated interferon‐beta (__IFN‐__Ξ²) gene transfer has been found to induce regression of experimental glioma. We have previously performed a pilot