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Phase I Clinical and Pharmacokinetic Study of the Novel Raf Kinase and Vascular Endothelial Growth Factor Receptor Inhibitor BAY 43-9006 in Patients With Advanced Refractory Solid Tumors

โœ Scribed by Strumberg, D.

Book ID
124101242
Publisher
American Society of Clinical Oncology
Year
2005
Tongue
English
Weight
207 KB
Volume
23
Category
Article
ISSN
0732-183X

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Phase I Clinical and Pharmacokinetic Stu
Phase I Clinical and Pharmacokinetic Study of the Novel Raf Kinase and Vascular Endothelial Growth Factor Receptor Inhibitor BAY 43-9006 in Patients With Advanced Refractory Solid Tumors
โœ Strumberg, D. ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› American Society of Clinical Oncology ๐ŸŒ English โš– 207 KB

## Purpose BAY 43-9006 is a novel dual-action Raf kinase and vascular endothelial growth factor receptor inhibitor that inhibits tumor cell proliferation and angiogenesis. This study established the safety and pharmacokinetics of BAY 43-9006 in 69 patients with advanced refractory solid tumors.