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Clinical phase I study of elpamotide, a peptide vaccine for vascular endothelial growth factor receptor 2, in patients with advanced solid tumors

โœ Scribed by Okamoto, Isamu; Arao, Tokuzo; Miyazaki, Masaki; Satoh, Taroh; Okamoto, Kunio; Tsunoda, Takuya; Nishio, Kazuto; Nakagawa, Kazuhiko


Book ID
119827163
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
131 KB
Volume
103
Category
Article
ISSN
1347-9032

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Phase I Clinical and Pharmacokinetic Stu
โœ Strumberg, D. ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› American Society of Clinical Oncology ๐ŸŒ English โš– 207 KB

## Purpose BAY 43-9006 is a novel dual-action Raf kinase and vascular endothelial growth factor receptor inhibitor that inhibits tumor cell proliferation and angiogenesis. This study established the safety and pharmacokinetics of BAY 43-9006 in 69 patients with advanced refractory solid tumors.