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Phase 2 trial of pemetrexed in children and adolescents with refractory solid tumors: A Children's Oncology Group study

✍ Scribed by Anne B. Warwick; Suman Malempati; Mark Krailo; Allen Melemed; Richard Gorlick; Matthew M. Ames; Stephanie L. Safgren; Peter C. Adamson; Susan M. Blaney

Book ID
112168242
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
95 KB
Volume
60
Category
Article
ISSN
1545-5009

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## Abstract ## BACKGROUND. Effective chemotherapy is lacking for most types of central nervous system (CNS) tumors in children. Temozolomide, an agent with activity against adult brain tumors, was investigated in children and adolescents with recurrent CNS tumors. ## METHODS. Temozolomide was ad