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Phase 1 trial of temozolomide plus irinotecan plus O6-benzylguanine in adults with recurrent malignant glioma

โœ Scribed by Jennifer A. Quinn; Sara Xiaoyin Jiang; David A. Reardon; Annick Desjardins; James J. Vredenburgh; Sridharan Gururangan; John H. Sampson; Roger E. McLendon; James E. Herndon II; Henry S. Friedman


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
129 KB
Volume
115
Category
Article
ISSN
0008-543X

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๐Ÿ“œ SIMILAR VOLUMES


Phase II trial of irinotecan plus celeco
โœ David A. Reardon; Jennifer A. Quinn; James Vredenburgh; Jeremy N. Rich; Sridhara ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 219 KB

## Abstract ## BACKGROUND In the current study, the authors report a Phase II trial of irinotecan (CPTโ€11), a topoisomerase I inhibitor active against malignant glioma (MG), with celecoxib, a selective COXโ€2 inhibitor, among MG patients with recurrent disease. ## METHODS Patients with MG at any