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Phase 1 trial of dasatinib plus erlotinib in adults with recurrent malignant glioma

โœ Scribed by David A. Reardon, James J. Vredenburgh, Annick Desjardins, Katherine B. Peters, Sith Sathornsumetee, Stevie Threatt, John H. Sampson, James E. Herndon II, April Coan, Frances McSherry, Jeremy N. Rich, Roger E. McLendon, Steven Zhang, Henry S. Friedman


Book ID
113076868
Publisher
Springer US
Year
2012
Tongue
English
Weight
234 KB
Volume
108
Category
Article
ISSN
0167-594X

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Phase II trial of irinotecan plus celeco
โœ David A. Reardon; Jennifer A. Quinn; James Vredenburgh; Jeremy N. Rich; Sridhara ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 219 KB

## Abstract ## BACKGROUND In the current study, the authors report a Phase II trial of irinotecan (CPTโ€11), a topoisomerase I inhibitor active against malignant glioma (MG), with celecoxib, a selective COXโ€2 inhibitor, among MG patients with recurrent disease. ## METHODS Patients with MG at any