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Pharmacology of diphenylhydantoin and carbamazepine action on voltage-sensitive sodium channels

✍ Scribed by Max Willow


Book ID
118390269
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
391 KB
Volume
9
Category
Article
ISSN
0166-2236

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Action potentials in mammalian nerve and muscle are generated by a stereotyped sequence of alterations in membrane conductance to monovalent cations [ 1,2]. The fundamental change that leads to the initiation of an action potential is a regenerative, but self-limited, increase in membrane conductanc