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Pharmacology of 5-Aza-2′-deoxycytidine (decitabine)

✍ Scribed by Richard L. Momparler


Book ID
117821872
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
210 KB
Volume
42
Category
Article
ISSN
1532-8686

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## Abstract ## BACKGROUND General and site‐specific DNA methylation is associated with tumor progression and resistance in several cancers, including chronic myelogenous leukemia (CML). Decitabine is a hypomethylating agent that has shown encouraging preliminary anti‐CML activity. This study evalu