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Epigenetic Therapy of Cancer With 5-Aza-2′-Deoxycytidine (decitabine)

✍ Scribed by Richard L. Momparler


Book ID
118735198
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
356 KB
Volume
32
Category
Article
ISSN
0093-7754

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## Abstract ## BACKGROUND General and site‐specific DNA methylation is associated with tumor progression and resistance in several cancers, including chronic myelogenous leukemia (CML). Decitabine is a hypomethylating agent that has shown encouraging preliminary anti‐CML activity. This study evalu