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Pharmacological Properties of Two New Antihistaminics of Prolonged Action

โœ Scribed by P'An, S.Y. ;Gardocki, J.F. ;Reilly, J.C.


Publisher
Elsevier
Year
1954
Weight
362 KB
Volume
43
Category
Article
ISSN
0095-9553

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## Abstract Reaction of 4โ€phenylโ€4__H__โ€1,2,4โ€triazoleโ€3โ€thione with ethyl bromoacetate has led to the formation of ethyl [(4โ€phenylโ€4__H__โ€1,2,4โ€triazolโ€3โ€yl)sulfanyl]acetate **1**, the structure of which was confirmed by Xโ€ray analysis. In the next reaction with 80% hydrazide hydrate, appropriate