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New synthesis of 1,4,2-dioxazoles and their pharmacological properties

✍ Scribed by Ned D. Heindel; William P. Fives; Richard A. Carrano


Publisher
John Wiley and Sons
Year
1977
Tongue
English
Weight
472 KB
Volume
66
Category
Article
ISSN
0022-3549

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Synthesis and antimicrobial and pharmaco
✍ Łukasz PopioΕ‚ek; Maria Dobosz; Anna Chodkowska; Ewa JagieΕ‚Ε‚o-WΓ³jtowicz; Urszula πŸ“‚ Article πŸ“… 2010 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 235 KB πŸ‘ 1 views

## Abstract Reaction of 4‐phenyl‐4__H__‐1,2,4‐triazole‐3‐thione with ethyl bromoacetate has led to the formation of ethyl [(4‐phenyl‐4__H__‐1,2,4‐triazol‐3‐yl)sulfanyl]acetate **1**, the structure of which was confirmed by X‐ray analysis. In the next reaction with 80% hydrazide hydrate, appropriate