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Pharmacological profile of KR-33028, a highly selective inhibitor of Na+/H+ exchanger

✍ Scribed by Yi-Sook Jung; Mi-Young Kim; Mi Jeong Kim; Kwang-Seok Oh; Kyu Yang Yi; Sunkyung Lee; Sung-eun Yoo; Byung Ho Lee

Book ID
113585978
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
554 KB
Volume
535
Category
Article
ISSN
0014-2999

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πŸ“œ SIMILAR VOLUMES

Dose-dependent pharmacokinetics of a new
Dose-dependent pharmacokinetics of a new Na+/H+ exchanger inhibitor KR-33028 in rats
✍ Young Hoon Kim; Sun Dong Yoo; You Sun Kim; Kyung Hee Lee; Hye Suk Lee πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 126 KB πŸ‘ 2 views

## Abstract The dose‐dependency of the pharmacokinetics of a new Na^+^/H^+^ exchanger inhibitor, KR‐33028 was evaluated in rats after intravenous and oral administration. After intravenous administration of KR‐33028 (1, 5, 10 and 20mg/kg doses), the systemic clearance (__Cl__) was reduced and __AUC