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Pharmacological profile of enantiomerically pure chiral muscarinic agonists: Desoxymuscarines

✍ Scribed by Marco De Amici; Clelia Dallanoce; Carlo De Micheli; Piero Angeli; Gabriella Marucci; Franco Cantalamessa; Lorenzo Sparapassi

Book ID
117172372
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
134 KB
Volume
67
Category
Article
ISSN
0024-3205

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πŸ“œ SIMILAR VOLUMES

Development of a pharmacological target
Development of a pharmacological target profile for muscarinic agonists
✍ Daniel V. Widzowski; Paul Bialobok; Kris E. Kucera; Roberta Mihut; Shawn Sitar; πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 178 KB

The purpose of these studies was to determine the levels of intrinsic activity in vitro at muscarinic receptor pharmacological subtypes (M 1 , M 2 , and M 3 ) that would optimize cognitive activity while minimizing acute adverse cholinergic effects in vivo. These levels of intrinsic efficacy at M 1