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Pharmacological Effects of Aqueous Extract from Valeriana adscendens

✍ Scribed by A. Capasso; V. De Feo; F. De Simone; L. Sorrentino

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 351 KB
Volume: 10
Category: Article
ISSN: 0951-418X
DOI: 10.1002/(sici)1099-1573(199606)10:4<309::aid-ptr850>3.0.co;2-j

No coin nor oath required. For personal study only.

✦ Synopsis

Federico I1 via Domenico Montesano 49 (80131) Naples, Italy A purified aqueous extract of Valerianu adscendens Trel. (Valerianaceae) was investigated for its pharmacological

profile. The extract did not exert significant changes on the nociceptive threshold in the hot plate and tail flick test and no effect was registered on the guinea-pig ileum. On the other hand, the extract significantly reduced both the locomotor activity and motor coordination of mice; it also prolonged sleep induced by pentobarbital, whereas no significant cataleptic response was observed. These effects may suggest neuroleptic-like properties.

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