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Pharmacological effects of a specific dopamine D-1 antagonist SCH 23390 in comparison with neuroleptics

✍ Scribed by A.V. Christensen; J. Arnt; J. Hyttel; J.-J. Larsen; O. Svendsen

Book ID
118340727
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
667 KB
Volume
34
Category
Article
ISSN
0024-3205

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To investigate the role of D, dopamine receptors in the discriminative stimulus effects of cocaine, two rhesus monkeys were trained in a two-lever, food-reinforced, drug discrimination paradigm to discriminate cocaine (0.2 rag/ kg, IM) from saline. Administration of various doses of cocaine resulted